Each tablet contains Pregabalin 75 mg and Nortriptyline 10 mg.

Neurica NT Tablets combine Pregabalin and Nortriptyline to provide effective management of neuropathic pain. The dual mechanism of action helps reduce pain transmission, improve nerve-related discomfort, and enhance quality of life in patients with peripheral neuropathic pain. The formulation offers both analgesic and neuromodulatory benefits for long-term neuropathic pain management.

Neurica NT Tablets are indicated for the treatment of neuropathic pain.

Neurica NT Tablets combine Pregabalin and Nortriptyline, which act through complementary mechanisms to relieve neuropathic pain. Pregabalin binds with high affinity to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system, reducing calcium influx into nerve terminals and decreasing the release of excitatory neurotransmitters involved in pain transmission. This results in significant anti-nociceptive activity and relief from neuropathic pain. Nortriptyline, a tricyclic antidepressant, inhibits the reuptake of serotonin and noradrenaline, thereby enhancing descending inhibitory pain pathways within the central nervous system. It also blocks voltage-gated sodium channels, which further contributes to its analgesic effects. Together, these mechanisms help reduce chronic neuropathic pain and improve functional outcomes.

The recommended dose is one tablet twice daily, or as directed by the physician.

Neurica NT Tablets are contraindicated in patients with known hypersensitivity to Pregabalin, Nortriptyline, or any component of the formulation.