Each sustained-release tablet contains Pregabalin 75 mg SR and Methylcobalamin 1500 mcg.

Pregator SR Tablets combine the prolonged analgesic action of Sustained-Release Pregabalin with the neurotrophic benefits of Methylcobalamin to help manage painful diabetic neuropathy. The formulation provides effective relief from neuropathic pain while supporting nerve regeneration, myelin repair, and healthy nerve function.

Pregator SR Tablets are indicated for the treatment of painful diabetic neuropathy in adult patients.

Pregator SR Tablets combine Sustained-Release Pregabalin and Methylcobalamin to provide symptomatic relief from neuropathic pain while supporting nerve repair. Pregabalin binds with high affinity to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system, reducing calcium influx into nerve terminals and decreasing the release of excitatory neurotransmitters involved in pain transmission. This mechanism produces significant anti-nociceptive effects and helps relieve neuropathic pain associated with diabetic peripheral neuropathy. Methylcobalamin (Mecobalamin), one of the biologically active forms of Vitamin B12, acts as an essential cofactor for B12-dependent methyltransferase enzymes, playing a key role in amino acid metabolism and one-carbon metabolic pathways. It also functions as a neurotrophic agent, promoting nerve cell growth, supporting myelin sheath maintenance, and facilitating the regeneration of damaged central and peripheral nerve tissues. Together, these ingredients help improve nerve function and provide comprehensive management of painful diabetic neuropathy.

The recommended dose is one sustained-release tablet once daily, with or without food, or as directed by the physician.

Pregator SR Tablets are contraindicated in patients with known hypersensitivity to Pregabalin, Methylcobalamin, or any component of the formulation.