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Bactoclav Dry Syrup / Tablets / Dispersible Tablets / Drops
Bactoclav Dry Syrup / Tablets / Dispersible Tablets / Drops
Bactoclav Dry Syrup / Tablets / Dispersible Tablets / Drops
Bactoclav Dry Syrup / Tablets / Dispersible Tablets / Drops
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Bactoclav Dry Syrup / Tablets / Dispersible Tablets / Drops

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Composition
Bactoclav Dry Syrup: Amoxycillin 200 mg + Clavulanic Acid 28.5 mg / Amoxycillin 400 mg + Clavulanic Acid 57 mg per suspension. Bactoclav 625: Amoxycillin 500 mg + Clavulanic Acid 125 mg Tablets. Bactoclav 1000: Amoxycillin 875 mg + Clavulanic Acid 125 mg Tablets. Bactoclav Dispersible Tablets: Amoxycillin 250 mg / 200 mg + Clavulanic Acid 125 mg / 28.5 mg. Bactoclav Drops: Amoxycillin 80 mg + Clavulanic Acid 11.4 mg.
Features / Experimentation
Broad-spectrum beta-lactam antibacterial combination effective against beta-lactamase producing organisms. Provides enhanced antibacterial coverage for respiratory tract, urinary tract, skin and soft tissue infections.
Indications
Indicated for the treatment of bacterial infections including sinusitis, otitis media, tonsillitis, acute and chronic bronchitis, lower respiratory tract infections, skin and soft tissue infections, urinary tract infections, pelvic infections, osteomyelitis, community-acquired pneumonia and acute bacterial sinusitis caused by susceptible organisms.
Pharmacodynamics
Amoxycillin is a semisynthetic penicillin that inhibits bacterial cell wall synthesis by interfering with peptidoglycan biosynthesis, leading to bacterial cell lysis and death. Clavulanic acid is a beta-lactamase inhibitor that protects amoxycillin from enzymatic degradation by beta-lactamase producing bacteria.
Dosage and administration
Adults: Bactoclav 625 – one tablet every 12 hours; severe infections – Bactoclav 1000 every 12 hours or Bactoclav 625 every 8 hours. Paediatric dosage is based on the amoxycillin component and body weight or as directed by the physician.
Contraindications
Contraindicated in patients with hypersensitivity to penicillins, clavulanic acid or formulation components and in patients with a history of severe hypersensitivity reactions to beta-lactam antibiotics including cephalosporins, carbapenems or monobactams.