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Dajio 10 Tablets
Dajio 10 Tablets
Dajio 10 Tablets
Dajio 10 Tablets
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Dajio 10 Tablets

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Composition
Each film-coated tablet contains Dapagliflozin 10 mg.
Features / Experimentation
Dajio 10 Tablets contain Dapagliflozin, a selective sodium-glucose co-transporter 2 (SGLT2) inhibitor that lowers blood glucose by promoting urinary glucose excretion. By inhibiting renal glucose reabsorption in the proximal tubules, Dapagliflozin provides insulin-independent glycemic control while offering additional metabolic benefits such as modest weight reduction and blood pressure lowering. Dajio is suitable as monotherapy in patients intolerant to Metformin and as add-on therapy with other antidiabetic medications, including insulin.
Indications
Dajio 10 Tablets are indicated for improving glycemic control in adults aged 18 years and older with type 2 diabetes mellitus. The medication may be used as monotherapy when diet and exercise alone do not provide adequate glycemic control and Metformin is considered inappropriate due to intolerance. It is also indicated as add-on combination therapy with other glucose-lowering medicinal products, including insulin, when diet, exercise, and existing treatment fail to achieve adequate glycemic control.
Pharmacodynamics
Dapagliflozin is a highly selective inhibitor of sodium-glucose co-transporter 2 (SGLT2), which is responsible for the majority of glucose reabsorption from the renal proximal tubules. By inhibiting SGLT2, Dapagliflozin reduces renal glucose reabsorption and promotes urinary excretion of excess glucose, thereby lowering plasma glucose concentrations independently of insulin secretion or insulin sensitivity. This mechanism contributes to improved glycemic control while also supporting modest reductions in body weight and blood pressure.
Dosage and administration
The recommended dosage is one 10 mg tablet taken orally once daily, with or without food, or as directed by the treating physician. Treatment should be continued alongside appropriate dietary modifications and regular physical activity to achieve optimal glycemic control.
Contraindications
Dajio 10 Tablets are contraindicated in patients with known hypersensitivity to Dapagliflozin or any component of the formulation. The medication is also contraindicated in patients with severe renal impairment, estimated glomerular filtration rate (eGFR) below 30 mL/min/1.73 m², end-stage renal disease (ESRD), or those undergoing dialysis.