Each tablet contains Cefixime 400 mg.

Gramocef-O 400 Tablets contain Cefixime, a third-generation oral cephalosporin antibiotic with broad-spectrum bactericidal activity against a variety of Gram-positive and Gram-negative pathogens. The once-daily formulation provides convenient dosing and improved patient compliance while delivering effective antibacterial coverage. Cefixime is widely used in the management of urinary tract infections, respiratory tract infections, and typhoid fever caused by susceptible bacterial organisms.

Gramocef-O 400 Tablets are indicated for the treatment of urinary tract infections (UTIs), respiratory tract infections (RTIs), and typhoid fever caused by susceptible bacteria.

Cefixime is a semi-synthetic, third-generation cephalosporin antibiotic that exhibits potent bactericidal activity against a broad spectrum of Gram-positive and Gram-negative microorganisms. It exerts its antibacterial effect by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins, resulting in disruption of cell wall integrity and bacterial cell death. This mechanism provides effective eradication of susceptible pathogens responsible for various community-acquired infections.

The recommended adult dosage is 400 mg once daily or as directed by the treating physician. The duration of therapy should be determined based on the severity of infection, clinical response, and physician assessment.

Gramocef-O 400 Tablets are contraindicated in patients with known hypersensitivity to Cefixime, other cephalosporin antibiotics, or any component of the formulation.