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Gramocef-O 50 / 100 Dry Syrup
Gramocef-O 50 / 100 Dry Syrup
Gramocef-O 50 / 100 Dry Syrup
Gramocef-O 50 / 100 Dry Syrup
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Gramocef-O 50 / 100 Dry Syrup

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Composition
Each 5 ml of reconstituted dry syrup contains Cefixime 50 mg or Cefixime 100 mg.
Features / Experimentation
Gramocef-O 50/100 Dry Syrup contains Cefixime, a third-generation oral cephalosporin antibiotic with broad-spectrum bactericidal activity against a wide range of Gram-positive and Gram-negative bacteria. The pediatric dry syrup formulation provides convenient dosing and improved compliance in children. Cefixime demonstrates excellent efficacy against common pathogens responsible for respiratory tract infections, urinary tract infections, biliary tract infections, and typhoid fever. Its once-daily or twice-daily dosing regimen offers flexibility and convenience in pediatric infection management.
Indications
Gramocef-O 50/100 Dry Syrup is indicated for the treatment of typhoid fever, urinary tract infections (UTIs), respiratory tract infections, and biliary tract infections caused by susceptible bacterial organisms.
Pharmacodynamics
Cefixime is a semi-synthetic, third-generation cephalosporin antibiotic that exhibits broad-spectrum bactericidal activity against a variety of Gram-positive and Gram-negative microorganisms. It acts by inhibiting bacterial cell wall synthesis through binding to specific penicillin-binding proteins, resulting in disruption of cell wall integrity and eventual bacterial cell death. Its potent antibacterial activity makes it effective against a wide range of clinically important pathogens.
Dosage and administration
The recommended pediatric dosage is 8 mg/kg/day of Cefixime suspension. This may be administered as a single daily dose or divided into two doses of 4 mg/kg every 12 hours. The dosage and duration of therapy should be determined by the physician based on the severity and nature of the infection. The safety and efficacy of Cefixime have not been established in children below 6 months of age.
Contraindications
Gramocef-O 50/100 Dry Syrup is contraindicated in patients with known hypersensitivity to Cefixime, cephalosporin antibiotics, or any component of the formulation.