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Ritecef OF Tablets
Ritecef OF Tablets
Ritecef OF Tablets
Ritecef OF Tablets
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Ritecef OF Tablets

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Composition
Each tablet contains Cefixime 200 mg and Ofloxacin 200 mg.
Features / Experimentation
Ritecef OF Tablets combine Cefixime, a third-generation cephalosporin antibiotic, with Ofloxacin, a broad-spectrum fluoroquinolone antibiotic, to provide enhanced antibacterial coverage against a wide range of Gram-positive and Gram-negative organisms. This combination is indicated for the treatment of typhoid fever and urinary tract infections in adults, offering dual mechanisms of action for effective bacterial eradication and improved clinical outcomes.
Indications
Ritecef OF Tablets are indicated for the treatment of typhoid fever and urinary tract infections (UTIs) in adult patients caused by susceptible bacterial pathogens.
Pharmacodynamics
Cefixime is a semi-synthetic, oral third-generation cephalosporin that exerts bactericidal activity by inhibiting bacterial cell wall synthesis, leading to bacterial cell death. Ofloxacin is a broad-spectrum fluoroquinolone antibiotic that inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, repair, and bacterial cell division. Together, the combination provides broad-spectrum antibacterial activity against susceptible organisms.
Dosage and administration
The recommended dosage is one tablet every 12 hours for 10 to 14 days, or as directed by the treating physician.
Contraindications
Ritecef OF Tablets are contraindicated in patients with known hypersensitivity to Cefixime, Ofloxacin, other cephalosporins, fluoroquinolones, or any component of the formulation.