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Dolowin Spas
Dolowin Spas
Dolowin Spas
Dolowin Spas
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Dolowin Spas

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Composition
Each tablet contains Aceclofenac 100 mg and Drotaverine 80 mg.
Features / Experimentation
Dolowin Spas is a combination of Aceclofenac, a nonsteroidal anti-inflammatory drug (NSAID), and Drotaverine, a potent antispasmodic agent. The formulation provides dual action by relieving pain and inflammation while simultaneously reducing smooth muscle spasm. It is particularly beneficial in painful musculoskeletal conditions accompanied by muscle spasm, improving patient comfort and restoring mobility.
Indications
Dolowin Spas is indicated for the treatment of muscular pain associated with muscle spasm in adults. It is useful in the management of acute musculoskeletal pain, soft tissue injuries, painful muscle spasms, and other inflammatory conditions requiring both analgesic and antispasmodic therapy.
Pharmacodynamics
Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) with potent anti-inflammatory and analgesic properties. It acts primarily by inhibiting cyclooxygenase (COX) enzymes, thereby reducing prostaglandin synthesis responsible for pain and inflammation. Drotaverine is an antispasmodic agent that inhibits phosphodiesterase enzymes in smooth muscle cells, resulting in increased cyclic AMP levels and correction of intracellular calcium imbalance. This leads to direct relaxation of smooth muscle, relieving spasm and the associated pain without producing anticholinergic effects.
Dosage and administration
The recommended dosage is one tablet twice daily, taken as one tablet in the morning and one tablet in the evening, or as directed by the treating physician.
Contraindications
Dolowin Spas is contraindicated in patients with known hypersensitivity to aceclofenac, drotaverine, or any component of the formulation. It should not be administered to patients with active or recurrent peptic ulcer disease or gastrointestinal hemorrhage, particularly those with two or more confirmed episodes of ulceration or bleeding.