Tramadol Hydrochloride 37.5 mg + Paracetamol 325 mg Tablets

Combination analgesic formulation providing effective short-term relief from moderate to severe acute pain. Combines opioid analgesic activity with analgesic and antipyretic properties for enhanced pain management.

Indicated for the short-term management (up to 5 days) of moderate to severe acute pain in adults.

Tramadol is a centrally acting synthetic opioid analgesic that inhibits the reuptake of norepinephrine and serotonin, thereby modulating pain transmission pathways. Paracetamol is a centrally acting analgesic and antipyretic agent with minimal anti-inflammatory properties that weakly inhibits prostaglandin synthesis within the central nervous system via COX-2 inhibition.

Initiate treatment with two tablets every 4–6 hours as needed for pain relief. Maximum dose: 8 tablets per day or as directed by the physician.

Contraindicated in patients with hypersensitivity to tramadol, paracetamol or formulation components and in situations where opioids are contraindicated, including acute intoxication with alcohol, hypnotics, narcotics, centrally acting analgesics, opioids or psychotropic drugs.