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Angiplat Capsules
Angiplat Capsules
Angiplat Capsules
Angiplat Capsules
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Angiplat Capsules

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Composition
Each capsule contains Glyceryl Trinitrate 2.5 mg / 6.5 mg.
Features / Experimentation
Vasodilator anti-anginal formulation designed for rapid relief and prophylaxis of angina pectoris associated with coronary artery disease. Helps improve coronary blood flow and reduce cardiac workload.
Indications
Indicated for acute relief and acute prophylaxis of angina pectoris due to coronary artery disease.
Pharmacodynamics
Nitroglycerin releases free radical nitric oxide (NO), which activates guanylate cyclase leading to increased cyclic guanosine monophosphate (cGMP) levels in vascular smooth muscle. This results in dephosphorylation of myosin light chains, smooth muscle relaxation, and vasodilation, thereby reducing myocardial oxygen demand and improving coronary circulation.
Dosage and administration
The usual adult dose is Glyceryl Trinitrate 2.5 mg or 6.5 mg three to four times daily or as directed by the physician.
Contraindications
Contraindicated in patients with hypersensitivity to nitrates, hypotension, hypovolemia, or raised intracranial pressure.