Each sustained-release capsule contains Diltiazem Hydrochloride 90 mg / 120 mg.

Sustained-release calcium channel blocker formulation designed for the management of hypertension and chronic stable angina. Helps improve exercise tolerance and reduce myocardial oxygen demand.

Indicated for the treatment of hypertension and for improving exercise tolerance in patients with chronic stable angina.

Diltiazem is a calcium channel antagonist that inhibits the influx of calcium ions into cardiac and vascular smooth muscle during membrane depolarization. It decreases sinoatrial and atrioventricular conduction, reduces vascular resistance, and exerts a negative inotropic effect, thereby lowering blood pressure and myocardial oxygen demand.

Capsules should be swallowed whole without chewing or crushing. Initial adult dose is 90 mg once daily, which may be increased to 120 mg based on blood pressure response and clinical requirement or as directed by the physician.

Contraindicated in patients with sick sinus syndrome without a functioning ventricular pacemaker, second- or third-degree AV block without a functioning ventricular pacemaker, hypersensitivity to diltiazem, hypotension (below 90 mm Hg), acute myocardial infarction with pulmonary congestion, and severe cardiac conduction disorders.