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Nebilong AM Tablets
Nebilong AM Tablets
Nebilong AM Tablets
Nebilong AM Tablets
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Nebilong AM Tablets

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Composition
Each tablet contains Nebivolol 5 mg + Amlodipine 5 mg.
Features / Experimentation
Nebilong AM Tablets combine Nebivolol, a highly selective beta1-adrenergic receptor blocker with vasodilatory properties, and Amlodipine, a long-acting calcium channel blocker. This dual-action combination provides effective 24-hour blood pressure control by reducing heart rate, cardiac workload, peripheral vascular resistance, and improving vascular relaxation. The once-daily formulation enhances treatment adherence and is suitable for the long-term management of hypertension.
Indications
Nebilong AM Tablets are indicated for the treatment of hypertension in adults requiring combination antihypertensive therapy.
Pharmacodynamics
Nebivolol is a selective β1-adrenergic receptor blocker that lowers blood pressure by reducing heart rate, decreasing myocardial contractility, suppressing renin release, reducing sympathetic nervous system activity, and promoting vasodilation, thereby decreasing peripheral vascular resistance. Amlodipine is a dihydropyridine calcium channel blocker that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. It acts as a peripheral arterial vasodilator, reducing systemic vascular resistance and lowering arterial blood pressure. The complementary mechanisms of these two agents provide effective and sustained antihypertensive activity.
Dosage and administration
The recommended dosage is one tablet orally once daily, or as directed by the physician. The tablet may be taken with or without food at the same time each day to maintain consistent blood pressure control.
Contraindications
Nebilong AM Tablets are contraindicated in patients with known hypersensitivity to Nebivolol, Amlodipine, or any component of the formulation, severe bradycardia, heart block greater than first degree, cardiogenic shock, decompensated cardiac failure, and sick sinus syndrome unless a permanent pacemaker is in place.